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Trixie is an unknown toxin/disease blamed for infecting local townspeople via the consumption of the contaminated water in Ogden Marsh, gradually transforming its victims into mindless, calculative, depraved, bloodthirsty killers preying on neighbors and families, including strangers seen in the 1973 original film The Crazies and the 2010 remake film The Crazies.

Trixie is apparently the most rarest, unknown, top-secret'Rhabdoviridae Prototype ' as supposedly Trixie may likely consider most definitely a 'bio-toxin'. Trixie is accidentally unleashed and tainted the water supply of 'Hopman Bog' of Ogden Marsh, Iowa directly via the U.S. governmental aircraft catastrophically crashing down as the fire ignites, losing management on the aircraft before crashing. By definition, Trixie is most defined as Some kind of mutated string of rabies that affects the brain and drives the infected victim insane, sending them on a murderous rampage. An injured Intelligence officer explains to Sheriff of Ogden Marsh, David Dutton, about the containment of the crashed aircraft he and Russell witnessed. The aircraft was en route to Texas to incinerate Trixie, demonstrating the U.S. authorized military is combating against what the U.S. government genetically engineered. He also explains how he tried attempting to help the parachuted pilot, found stuck into the branches, who had died and was too late. The parachuted pilot, was found underwater and covered in an oily like substances which may have been Trixie which had spilt out when the aircraft crashed. Accordingly,Trixie was designed to destabilize the population and wipe out target areas. The infected were overcome with insanity and then death when having reached the incubation period of 48 hours. Symptoms included hallucination, paranoia, repetitive manners/speech and statue-like behavior.

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